磁共振成像皮层下高信号病灶的临床分析

Clinical Analysis of Hyperintense Subcortical Lesions on Magnetic Resonance Imaging

MRI颅脑扫描经常发现皮层下高信号病灶(HSL),其成因和临床意义常难于解释。本文收集524例MRI扫描有HSL的病例,按MRI影像学进行分析,用多元回归分析HSL的严重程度和相关因素的关系,对其成因、临床意义进行评价。结果表明:HSL主要由血管源性和非血管源性所致,其严重程度与年龄、中风史、高血压、脑萎缩密切相关,和神经科症状、体征、智能之间不相关。

Hyperintense subcortical lesions (HSL) are frequently identified on MRI. The etiology and clinical correlation of these lesions remain unknown. In this report, 524 cases on MRI had HSL. HSL were graded according to MRI findings, and their pathogenesis and clinical information were also assessed. The results suggest ed that HSL may be caused by vascular or non-vascular diseases. HSL. were found to be associated with age, stroke, hypertension (P<0.01), and no correlation with neurological symptoms and signs, including intelligence.