年龄对女性髂骨骨小梁结构的影响

Aged-related Changes in Trabecular Architectures of Iliac Crest in Normal Chinese Women

研究14名妇女髂骨骨小梁结构与年龄的关系。将海绵骨结构按骨小梁排列方式分为结节、游离端和各种形式的小梁,在光学显微镜下,用MOP-Videoplan图象分析仪进行测量。随年龄增加、结节数、皮质来源小梁数、骨小梁总数、结节数与游离端之比和结节间小梁长度占全部骨小梁长度的百分比均明显下降,游离骨小梁长度增加,但单位面积内游离端的数目无明显变化。结果表明,随着年龄增加、骨小梁数目减少、结构破坏。本文讨论了骨侵蚀和骨丢失的方式。

In the present study trabecular architecturres of iliac crest were investigated in 15 normal Chinese women. Based upon the modes of trabecular arrangement, the cancellous bone was classified as node, free end and trabecular strut, By light microscopy the trabecular structures were evaluated with semi-automatic Mop-Videop-lan. The results showed that with aging the number of trabecular lenghth between the nodes over the total trabecular lenghth were significantly declined. In contrast, the lenghth of free strut was increased. It indicated that with aging the number of trabecular struts was reduced, leading to trabecular destruction. The models of bone erosion and bone loss were discussed.