原因不明发热198例分析

Clinical Analysis of 198 Cases of Fever of Unknown Origin

对198例原因不明发热(Fever of Unknown Origin FUO)患者行病原学、血清学、组织学等方法检查确定其诊断。结果为感染性疾病占首位(51.01％),且以局限于某一器官感染为多,血管一结缔组织疾病占25.76％,肿瘤占9.60％,药物热占4.54％,出院或死亡时仍诊断不清者占9.09％。肿瘤在FUO中比例呈下降趋势(P<0.05),可能由于新的诊断仪器如B超、CT等在临床广泛使用,使肿瘤更容易被早期发现。就FUO的诊断方法进行了探讨,认为详细询问病史、仔细全面查体、选择针对性强的辅助检查以及活体组织病理检验,对缩短FUO诊断的时间,提高其确诊率是有益的。

From Jan. 1989 to Dec. 1993, 198 Patients hospitalized for fever of unknown origin (FUO) were studied. They were diagnosed with the methods of aetiology, serology, histology, etc. Their ultimate diagnoses were infectious diseases, tumors, collagen and vascular-connective tissue diseases. Infectious diseases amounted to 51.01%, most of which were localized in certain organs, tumors 9.60%, collagen and vascular-connective tissue diseases 25.76%, drug-induced fever 4.54%. Patients who remained undiagnosed when they were discharged from the hospital or died accounted for 9.09%. The main feature of this series of cases was high frequency of infectious diseases. The proportion of tumors had tendency to go down in FUO in the recent ten years (P<0.05). The diagnostic methods of FUO were discussed in detail.