摘要
采用平皿打孔法测定中草药大黄和黄柏对临床分离的致肾盂肾炎大肠杆菌132和136的抗菌活性,结果均为耐药。继而,分别取不同浓度的大黄和黄柏处理上述菌株,利用血凝试验检测这两种药物对致肾盂肾炎大肠杆菌粘附特性的抑制作用。结果表明两种中草药对其均有抑制作用,大黄稍强于黄柏,提示中草药抗菌作用的机制可能与其抑制粘附有关。
The susceptibilities of uropathogenic E. coli strains 132 and 136 isolated from urine of patients with pyelonephritis to anti-infectious Chinese medicinal herbs, Pheum palmatum (大黄) and Phellodendron (黄柏), were examined by plate-digged method. The results indicated that the two multiple resistance strains were also resistant to these Chinese herbs. Meanwhile, the effects of the different concentrations of Pheum Palmatum and Phellodendron on the adherence of uropathogenic E. coli were investigated by hemagglutination test. The results showed that the above Chinese medicinal herbs possessed the adherence inhibiting efficiency on the tested strains 132 and 136, the effect of Pheum palmatum being slightly stronger than that of Phellodendron. It was suggested that the antibacterial activities of Chinese medicinal herbs may be related with their adherence inhibiting effect.
出处
《天津医药》
CAS
1994年第10期579-581,共3页
Tianjin Medical Journal
基金
国家自然科学基金
