女性更年期与甲状腺机能减退

Menopausal Women and Hypothyroidism

报告1990年10月～1991年7月在国外进修期间接诊的305例女性更年期患者,通过测定促甲状腺激素(TSH)、促甲状腺素释放激素(TRH)、甲状腺球蛋白抗体(TGA)、甲状腺微粒抗体(TMA)及临床观察,发现TSH升高的阳性率为12.13％。119例TSH正常者中有16例抗TGA或/和抗TMA阳性,阳性率为13.45％。TSH水平升高患者有58.33％的抗体阳性。由此可见,血清抗体阳性可能预示着甲减症的发生。本报告中女性更年期甲减症患病率为10.81％,呈高发趋势,应当引起从事更年期门诊工作人员的注意,特别注意测定TSH。

Three hundred and five menopauisal women from 43 to 64 years old had taken laboratorial examination in TSH, TRH, TGA and/or TMA. There were 37 cases whose serum TSH level elevated in this study, which showed that the incidence was 12.13%. -There were 16 cases whose TGA and/or TMA were positive in 119 cases of normal level TSH It means that positive rate of antibody was 13.45%. In the patients with high level TSH, 58.33% (14/24 cases) of them had positive serum antibody. The results indicated that positive serum antibody could -suggest existence of hypo-thy roidism. In this study, the incidence of hypothyroidism in menopausal women was 10.81% (33/305 cases), to which researchers who engage in the menapausal study shall pay attention.