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不同浓度异氟醚对大鼠海马乙酰胆碱释放的影响 被引量：1

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摘要 麻醉药可影响颅内神经递质的水平,如多巴胺、去甲肾上腺素和乙酰胆碱(Ach)[1].异氟醚对颅内神经递质的影响尚未完全阐明.本研究拟观察不同浓度异氟醚对大鼠海马Ach释放的影响.
作者 吴安石 岳云 龙健晶 王云
机构地区 首都医科大学附属北京朝阳医院麻醉科
出处 《中华麻醉学杂志》 CAS CSCD 北大核心 2005年第1期58-59,共2页 Chinese Journal of Anesthesiology
关键词 异氟醚 大鼠 海马 乙酰胆碱 麻醉药
分类号 R965 [医药卫生—药理学]
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参考文献6

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同被引文献14

  • 1杨国军,陈志宏,庞晓静.衰老大鼠海马单胺类神经递质含量的变化[J].承德医学院学报,2005,22(3):201-203. 被引量：1
  • 2汪海林,邹汉法,孙生才,张玉奎.微透析取样技术及其在生化分析中的应用[J].色谱,1996,14(6):441-446. 被引量：7
  • 3Wenk GL, Pierce DJ, Struble R, et al. Age-related changes in multiple neurotransmitters systems in the monkey brain. Neurobiol Aging, 1989,10 : 11-19.
  • 4Lars Backman, Lars Nyberg, Ulman Lindenberger, et al. The correlative triad among aging, dopamine, and cognition : current status and future prospects . Neuros Biobeh Rev, 2006, 30 : 791- 807.
  • 5Li SC, Ulman Lindenberger, Sverker Sikstom. Aging cognition: from neuromodulation to representation. Trends Cognit Sci, 2001, 5 : 479-486.
  • 6Hasselmo ME. Neuromodulation: acetylcholine and memory consolidation. Trends Cognit Sci, 1999, 3 : 351-359.
  • 7Bartus RT. On neurodegenerative diseases, models, and treatment strategies: lessons learned and lessons forgotten a generation following the cholinergic hypothesis. Exp Neurobiol, 2000, 163: 495 -529.
  • 8Lazaris A, Bertrand F, Lazarus C, et al. Baseline and 8-OHDPAT-indnced release of acetylcholine in the hippocampus of aged rats with different levels of cognitive dysfunction. Brain Res, 2003, 967:181-190.
  • 9Tottori K, Nakai M, Uwahodo Y, et al. Attenuation of scopolamine-induced and age-associated memory impairments by the sigma and 5-hydroxytryptamine (1 A ) receptor agonist OPC- 14523 ( 1-[ 3-[ 4-( 3-chlorophenyl )-1-piperazinyl propyl ]-5- methoxy-3, 4-dihydro-2 [ 1 H ] -quinolinone monomethanesulfonate). J Pharmacol Exp Ther, 2002, 301 : 249- 257.
  • 10Muller M. Science, medicine, and the future: microdialysis. Bri Med J, 2002, 324: 588-591.

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中华麻醉学杂志
2005年 第1期

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