血液病患者血浆中分子物质含量及其临床意义的探讨

The Contents of MMS and lts ClinicalSignificance in The Plasma of Patients withHematological Disorder

应用紫外吸收法，检测４８例血液病患者血浆中分子物质（ＭＭＳ）含量，并以２０１名健康人做对照。同步观察了患者血肌酐、尿素氮，并采用治疗前后比较。结果表明：再障组ＭＭＳ正常；混合型营养住贫血、淋巴瘤及骨髓增生异常综合征（ＭＤＳ）减低，多发性骨髓瘤治疗前减低、化疗缓解后恢复正常，白血病组急性期增高，化疗缓解后恢复正常而恶化或复发后又明显增高。说明（ＭＭＳ）可以作为白血病的辅助诊断，观察疗效及判断预后的指标。

sing the method of ultraviolet , we mea-sured the contents of MMS in 48 patients withhematological disorder in contrast to 201 nor-mal persons. At the same time, we observedthe blood creatine and blood urea nitrogen inthe patients before and after the chemothera-py. The results demonstrated that the con-tents of MMS in the patients with aplasticanemia were normal, and in the patients withmixed nutritional anemia , lymphoma andmyelodysplastic syndrome were lower and inthe patients with multiple myloma were alsolower before chrinotherapy but became normalin remission period, The contents of MMS inleukemia were higher but became normal afterchemotherapy in remission period and it gotmuch higher when the situation show deterio-rative or the disease relapsed. So the studysuggested that the contents of MMS inleukemia patients can be used as an index ofaccessory diagnosis, the supervision ofchemotherapy effect and the prognosis of thepatients.