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度他雄胺的药理作用与临床应用 被引量:4

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摘要 度他雄胺是第2代5α还原酶抑制药,通过查阅文献,综述介绍度他雄胺的药理作用、临床应用、用法用量、不良反应及药物相互作用。
作者 顾国良 袁峰
出处 《医药导报》 CAS 2005年第3期214-215,共2页 Herald of Medicine
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参考文献5

  • 1Foley C L, Bott S R, Shergill I S, et al. An update on the use of 5-alpha-reductase inhibitors[J]. Drugs Today (Barc), 2004 ,40(3):213 -223.
  • 2Roehrborn C G, Boyle P, Nickel J C ,et al. Efficacy and safety of a dual inhibitor of 5-alpha-reductase types 1 and 2 (dutasteride) in men with benign prostatic hyperplasia [J] . Urology, 2002, 60 ( 2 ):434 -441.
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  • 5Clark R V, Hermann D J, Cunningham G R, et al. Marked suppression of dihydrotestosterone in men with benign prostatic hyperplasia by dutasteride, a dual 5-alpha-reductase inhibitor[J]. J Clin Endocrinol Metab, 2004,89(5 ) :2179 - 2184.

同被引文献29

  • 1李启彬,巩新玉,曹云峰,李青丽.度他雄胺的合成分析[J].中国医药指南,2008,6(20):153-154. 被引量:3
  • 2陈雯秋.清洁验证中的分析方法验证[J].中国药业,2005,14(4):17-19. 被引量:25
  • 3Clark R V, Hermann D J, Cunningham G R, et al. Marked suppression of dihydrotestosterone in men with benign prostatic hyperplasia by dutasteride, a dual 5a-reductase inhibitor[J]. J Clin Endoerinol Metab, 2004, 89(5): 2179-2184.
  • 4Reddy M S, Srinivasulu G, Srinivas K, et al. Process for the preparation of 17beta-N-[2,5 -bis(trifluoromethyl)phenyl] carbamoyl-4-aza-5-alpha-androst- 1-en -3-one[P]. US: 2005059692A1, 2005-3-17.
  • 5Batchelor K W, Frye S V. Androslenone derivative[P]. WO: 9507927: 1995-3-23.
  • 6Bartsch G, Rittmaster R S, Klocker H. Dihydrotestosterone and the concept of 5a-reducyase inhibition in human benign prostatic hyperplasia[J]. World J Urol, 2002, 19(6): 413-425.
  • 7Roehrborn C G, Boyle P, Nickel J C, et al. Efficacy and safety of a dual inhibitor of 5a-redueyase types 1 and 2(dutasteride) in men with benign prostatic hyperplasia[J]. Urology, 2002, 60(3): 434-441.
  • 8Andriole G L, Bostwick D G, Brawley O W, ctal. Effect of dutasteride on the risk ofprostatecancer[J]. N Eng J Med, 2010, 362(13): 1192-1202.
  • 9国家食品药品监督管理局药品生产验证指南[M].北京:化学工业出版社,2003.
  • 10Liu G P,Zhang D R,Jiao Y.Comparison of different methods for preparation of a stable riccardin D formulation via nano-technology[J].Int J Pharm,2012,422:516-522.

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