摘要
综述了放射免疫分析和放射免疫显像在癌症诊断中研究和应用的新进展.着重介绍了肿瘤标志物体外检测的意义及其特异性受到的主要局限;讨论了人抗鼠抗体的产生、靶/非靶放射性活度比值的提高、放射性核素的选择等方面需要解决的问题和研究发展.
The recent advance of study and application for radioimmunoassay and radioimmunoimaging in diagnosis of cancer is summarized. Significance of tumour marker detection by in vitro method and main limitation of their specificity are introduced. The effect of human antimouse antibody, improvement of T/NT ratio, choice of radionuclides and application of monoclonal antibody are discussed emphatically.
出处
《同位素》
CAS
北大核心
1994年第4期238-243,共6页
Journal of Isotopes
关键词
放射免疫测定
肿瘤标志物
癌
诊断
radioimmunoassay radioimmunoimaging tumour marker monoclonal antibody
