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抗高血压药物特点及其经济学评价(一) 被引量:2

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摘要 近20年来,针对高血压的循证医学研究层出不穷,极大推动了医学界对高血压的认识和治疗观念的更新.根据2004年10月发表的"中国居民营养与健康状况调查",我国高血压的患病率为18.8%,估计全国患病人数1.6亿多.脑卒中、心肌梗死、冠心病、终末期肾病以及心力衰竭的发病率与高血压密切相关.
出处 《中华医学信息导报》 2005年第4期16-16,共1页 China Medical News
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  • 1梁远红,林曙光,周燕,王晋明,王芳,余细勇.运动训练联合基因治疗对肾性高血压大鼠肾功能的影响[J].中华肾脏病杂志,2007,23(9):575-578. 被引量:1
  • 2MANCIA G, DE BACKER G, DOMINICZAK A, et al. 2007 guidelines for the Management of Arterial hypertension:the task force for the management of arterial hypertension of the european society of hypertension (ESH) and of the european society of cardiology (ESC) [J]. J Hypertens, 2007 25 (6): 1105-1187.
  • 3LINDHOLM L H, CARLBERG B, SAMUEISSON O. Should β blockers remain first choice in the treatment of primary hypertension? A meta-analysis[J]. Lancet, 2005, 366 (9496) : 1545-1553.
  • 4ZHANG Y C, BUI J D, SHEN L, et al. Antisense inhibition of β1-adrenergic receptor mRNA in a single dose produces a profound and prolonged reduction in high blood pressure in spontaneously hypertensive rats [J]. Circulation, 2000, 101 (6): 682-688.
  • 5LIANG Y H, LIN S G, ZHOU Y, et al. Beta-1 adrenergic receptor antisense oligodeoxy-nucleotides ameliorates left ventricular remodeling in 2-Kidney, 1-Clip rats[J]. J Biomed Sci, 2007, 14 (1): 155-164.
  • 6PHILLIPS M I, KIMURA B. Gene therapy for hypertension: antisense inhibition of the renin-angiotensin system[J]. Methods Mol Med, 2005, 108: 363-379.
  • 7CHOI W J, KIM J K, CHOI S H, et al. Low toxicity of cationic lipid-based emulsion for gene transfer[J]. Biomaterials, 2004, 25 (27): 5893-5903.
  • 8JARAD G, SIMSKE J S, SEDOR J R, et al. Nucleic acid-based techniques for post-transcriptional regulation of molecular targets [J ]. Curt Opin Nephrol Hypertens, 2003, 12 (4): 415-421.
  • 9KAGIYAMA S, QIAN K, KAGIYAMA T, et al. Antisense to epidermal growth factor receptor prevents the development of left ventricular hypertrophy[J]. Hypertension, 2003, 41 (3): 824-829.
  • 10张廷杰,范丽明,张静.高血压联合用药现状与评价[J].心血管病学进展,2000,21(3):147-150. 被引量:49

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