盆腔炎颗粒对小鼠感染模型的体内抗菌作用观察

Observation of antibacterial effect of Penqiangyan granule in infected mice body

目的 观察盆腔炎颗粒在体内的抗菌作用。方法 用临床分离的脆弱类杆菌、大肠杆菌、金黄色葡萄球菌分别注入小鼠腹腔 ,观察 2周内各组小鼠的死亡情况。再以同样的方法给小鼠注入不同菌液后 7天 ,给感染小鼠注入不同剂量的盆腔炎颗粒、蒸馏水、复方杏香兔耳风颗粒进行对照。结果 盆腔炎颗粒中、高剂量对小鼠感染脆弱类杆菌、大肠杆菌和金黄色葡萄球菌均有较好的抗感染作用。结论 盆腔炎颗粒中、高剂量对脆弱类杆菌、大肠杆菌、金黄色葡萄球菌感染的小鼠有较好的的抗感染作用 ,且随剂量增加作用加强。

Objective To observe antibacterial effect of Penqiangyan granule in vivo.Methods Bacillus fragilis, bacillus coli and golden staphylococcus separated from clinical were injected into the abdominal cauity of mice respectively to observe the death rate of each group during two weeks. Then the mice infected by the above-mentioned method were given Penqiangyan granule, distilled water and Xingxiangtuerfeng granule at different dosage one week later.Results A medium dose of Penqiangyan granule had good anti infective effect on mice infected by bacillus fragilis, bacillus coli and golden staphylococcus. Conclusion Both medium and higher dose of Penqiangyan granule showed good anti infective effect on mice infected by bacillus fragilis, bacillus coli and golden staphylococcus. Moreover the effect improved with the increase of dosage.