脑梗死患者睡眠呼吸改变与中医证型的相关性研究

Study on Correlativity between Changes of Respiratory at Sleep and TCM Syndrome Types in the Patient of Cerebral Infarction

目的:观察脑梗死、脑梗死兼睡眠呼吸紊乱患者的中医辨证分型特点。方法:对住院治疗的90例脑梗死患者,在入院72小时内行多导睡眠图监测,作出睡眠呼吸障碍诊断,并对所有的患者按中风(中经络)分为络脉空虚、风邪入中,肝肾阴虚、风阳上扰,痰热腑实、风痰上扰3型。结果:脑梗死患者睡眠结构紊乱,血压变化大,心脏变异性较差,血氧饱和度下降。痰热腑实、风痰上扰型患者的呼吸暂停指标最高,而脉络空虚、风邪入中型基本正常。结论:脑梗死(特别是痰热腑实、风痰上扰型)患者与睡眠呼吸紊乱关系密切。

Objective:To observe characteristics of TCM syndrome types in the patient of cerebral infarction,and cerebral infarction with respiratory disorder at sleep.Methods:90 in-patients of cerebral infarction were monitored by polychannel sommocinematogram (PSG)within 72 hours of admission,which were used as diagnosis of respiratory disturbance at sleep,and all of the patients with apoplexy involving the channels and collaterals were divided into 3 types,collaterals hollow and pathogenic wind attacking the interior;Yin-deficiency of the liver and kidney,and wind-Yang stirring upper,hot phlegm and excess of Fu-organs,and wind- phlegm stirring the upper.Results:The patient had sleep structure disorder,with large change of blood pressure and lower heart variety,and decrease of degree of blood oxygen saturation.The apnea indexes were the highest for the patient with phlegm-heat hollow-organ excess,wind-phlegm stirring the upper,and baic normal for collateral hollow and pathogenic wind attacking the interior.Conclusion:There is close relation of cerebral infarction,especially in the patient of hot phlegm and excess of Fu-organ, with respiratory disorder at sleep.