心肌炎和冠心病患者左室功能的改变

THE CHANGES OF LEFT VENTRICULAR FUNCTION IN PATIENTS WITH MYOCARDITIS OR CORONARY ARTERY DISEASE

本文采用同步描记心电图(ECG)、心音图(PCG)。心阻抗一阶导数图(first derivativeof impedance cardiogram,FDICG)、颈动脉搏动图(CPT)和心尖搏动图(ACG)的方法,以正常人为对照,研究心肌炎和冠心病患者左室功能的改变。结果显示心肌炎患者缓慢充盈波(SFW)和快速充盈波(RFW)的比值显著增加(P<0.001),心房收缩增强;而冠心病患者各项心功能指标均下降,致使心泉血量显著减少。从而提示心肌损伤后,首先影响早期舒张功能,而后才累及收缩功能。

Left ventricular function was determined in 28 normal subjects (group A), 33 patients with myocarditis (group B) and 50 patients with coronary artery disease (group C) by simultaneously recording of clcctrocardiogram(ECG), phonocardiogram (PCG), first derivative of electrical impedance cardiogram(TPG), carotid pulse trace (CPT), and apcxcardiogram (ACG). The results showed that (1) the ratio of slow filling phase /rapid filling phase was significantly increased (P<0.001) and atrial contraction more powerfully in group B, (2)all index of cardiac function were depressed and significantly reduced on stroke volume and cardiac output in group C. These findings suggest that when mycardium is injured left ventricular diastolic function is firstly disturbed, especially in early diastole , Which is then followed by disturbance of systolic function.