血清甘氨胆酸测定对肝硬化Child分级的临床意义

The Clinical Significance of Serum Cholylglycine Determination on The Chi- Id's Classification of Patients witn Cirrhosis

本文对58例肝硬化患者在 Child 分级下进行空腹及餐后血清甘胆酸(SCG)值测定。结果肝硬化患者按 Child分级的 A、B、C 三组空腹及餐后 SCG 较正常对照组(77人)均显著升高(P<0.01),并且 SCG 值随着 Child 分级的增高而上升(P<0.01)。空腹及餐后 SCG 值与血清白蛋白呈显著负相关(P<0.001),与血清胆红素呈显著正相关(P<0.01)。提示肝硬化患者测定空腹及餐后 SCG 值对 Child 分级具有一定临床价值,可作为 Child 分级的一个补充指标。

The levels of fasting serum cholyl- glycine(SCG)(glycocholic acid)of 58 patients and postprandial SCG of 44 patients with cirrhosis under Child's classification and 77 normal subjects se- rved as controls were studied.The res- ults showed that the fasting and postp- randial SCG levels were markedly inc- teased in A,B,C groups of Child's cla- ssification(P<0.01).The levels of SCG increased togather going-up of Child's classification of cirrhosis(P< 0.01).The levels of SCG showed app- arently positive correlated with serum bilirubin (P<0.01),and apparently negative correlated with serum albumin (P<0.001).It showed that fasting and postprandial SCG levels determination were valuable for the Child's elassifi- cation of cirrhosis.