纳络酮防治要求儿科观察的新生高危儿呼吸功能不全

Naloxone can prevent and cure respiratory failure of neonate that have factors endangering their life and need watching at department of pediatrics.

目的探讨用纳络酮防治要求儿科观察的新生高危儿呼吸功能不全.方法2000年5月～2004年5月要求儿科观察的新生高危儿100例,平均随机分为两组,A组用纳络酮0.10～0.30mg、B组用CDPC(胞二磷胆碱)0.10～0.20 g分别加入10%GS 40～80 ml静脉滴注,每日一次.结果A组总有效率约92%,B组总有效率约64%,两组疗效经x2检验,差异有高度显著性.结论纳络酮防治要求儿科观察的新生高危儿呼吸功能不全效果较好.

Objective To explore the use of Naloxone in prevention and cure of respirator failure of neonate that have factors endangering their life and need watching at department of pediatrics.Methods 100 cases from May.2000 to May.2004 were enrolled in the study.They wee divided two groups.Group A was given Naloxone solution each day and Group B was given CDPC.Results The overall effective rate of group A was92% while in group B it was 64%.The two curative effect can compare by chi-square test.There was highly signinficant difference between group A and group B.Conclusion Using Naloxone in prevention and cure of respiratory failure of neonate is better.