颈动脉粥样硬化斑块稳定性与C反应蛋白的关系

Relation between the stabilization of carotid atherosclerosis plaque and C-reactive protein

目的探讨颈动脉粥样硬化斑块稳定性与C反应蛋白(CRP)的关系。方法用高分辨超声技术检测97例患者颈动脉斑块,并将其分组。A组:颈动脉无斑块发生;B组:颈动脉有稳定斑块;C组:颈动脉有不稳定斑块。检测各组患者血清CRP水平。结果CRP在A组为(3.53±1.23)mg/L,在B组为(4.29±2.50)mg/L,在C组为(7.35±9.81)mg/L。B组与A组比较无显著性差异,C组与A组、C组与B组比较有显著性差异。结论不稳定斑块患者血清CRP增高,血清CRP与斑块稳定性相关。

Objective To investigate the relationship between the stabilization of carotid atherosclerosis plaques and level of C reastive protein(CRP) Methods The carotid atherosclerosis plaques were examined in 97 patients with high resolution ultrasonography Then the patients were divided into three group,group A:30 patients with no plaque;group B:33 patients with stable plaques;group C:34 Patients with unstable plaques The plasma CRP was detected in every patient Results The plasma CRP in group A:3 53±1 23mg/L,group B:4 29±2 5mg/L,group C:7 35±9 81mg/L The level of CRP in group C was significant different compared with group A and group B Conclusions The plasma CRP level significantly increases in patients with unstable plaques The plasma CRP is correlated with the stabilization of carotid atherosclerosis plaques