摘要
目的 研究糙叶败酱Patrinia scabra中的木脂素类化学成分。方法 应用柱色谱和HPL C法分离纯化,通过光谱(IR、MS、1 H- NMR、1 3C- NMR、DEPT、HMQC和HMBC)鉴定其化学结构。结果 分离并鉴定了4个木脂素类化合物:松脂醇- 4 ,4′-二- O-β- D -葡萄糖苷( )、罗汉松脂酚- 4 ,4′-二- O-β- D -葡萄糖苷( )、落叶松脂醇- 4′- O-β-D-葡萄糖苷( )、落叶松脂醇- 4 - O- β- D-葡萄糖苷( )。结论 化合物 ~ 均为首次从该属植物中分得,并首次给出化合物 的核磁共振数据。
Objective To study the lignans in Patrinia scabra. Methods The constituents were separated and purified by column chromatographies with silica gel, RP-silica gel, and Sephadex LH-20. Their structures were elucidated on the basis of spectral data (IR, MS, 1H-NMR , 13 C-NMR , DEPT, HMQC and HMBC). Results There were four lignans obtained from P. scabra with the structures identified as pinoresinol-4, 4′-di-O-β-D-glucopyranoside (Ⅰ), and matairesinol-4, 4′-di-O-β-D-glucopyranoside (Ⅱ), lariciresinol-4′-O-β-D-glucopyranoside (Ⅲ), and lariciresinol-4-O-β-D-glucopyranoside (Ⅳ). Conclusion All the four compounds are found in P. scabra for the first time. The NMR data of compound Ⅱ are given first.
出处
《中草药》
CAS
CSCD
北大核心
2005年第3期338-340,共3页
Chinese Traditional and Herbal Drugs
基金
国家高技术研究发展计划 (863计划 ) (2 0 0 3 AA2 Z3 5 0 7)
上海市科技发展基金资助 (0 2 DZ1914 7
0 1DJ190 10 )
关键词
糙叶败酱
木脂素
化学成分
Patrinia scabra Bunge
lignans
chemical constituent