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内皮抑素研究新进展 被引量:1

Research Advances of Endostatin
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摘要 内皮抑素通过特异地抑制血管内皮细胞的生长来抑制肿瘤的生长和转移,是一种很有前景的抗肿瘤药物。该文就内皮抑素的结构与功能、作用机制、提取与应用等方面进行综述。
出处 《中国肿瘤》 CAS 2005年第3期168-170,共3页 China Cancer
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  • 1任明华,刘兴汉,闫玉清,姚鸿超,王淑晶,徐建勇.重组人内皮抑素的表达、纯化、复性方法研究[J].中国肿瘤,2003,12(10):598-601. 被引量:5
  • 2Folkman J.Role of Oangiogenesis in tumor growth and metastasis [J].Semin Oncol,2002,29 (6 Suppl 16):15-18.
  • 3John H, Forssmann WG. Determination of the disulfide bond patern of the endogenous and recombinant angiogenesis inhibitor endostatin by mass spectorometry [J].Repid Commun Mass Spectrom,2001,15(14) :1222-1228.
  • 4Kasai S ,Nagasawa H, Shimamura M, et al. Design and synthesis of antiangiogenic/ heparin-binding arginine dendrimer mimicking the surface of endostatin [J].Bioorgan Med Chem Let ,2002,12;951-954.Sasaki T, Fukai N,Mann K,et al.
  • 5Structure,function and tissue forms of the globular domain of the cterminal globular domain of collagen X Ⅷ containing the angiogenesis inhibitor endostatin[J]. EMBO J,1998,17(15): 4249-4256.
  • 6Zatterstrom UK, Felbor U, Fukai N, et al. Collagen XⅧ/endostatin structure and functional role in angiogenesis [J].Cell Struct Funct,2000,25(2):97-101.
  • 7Karumanchi SA, Jha V, Ramchandran R, et al. Cell surface glypicans are low-affinity endostatin receptors [J].Mol Cell, 2001,7 (4):811-822.
  • 8Lee SJ,Jang JW, Kim Ym, et al.Endostatin binds to the catalytic domain of matrix metalloproteinase-2 [J].FEBS Lett, 2002,519(1-3): 147-152.
  • 9Wickstrom SA, Veikkola T, Rehn M,et al. Endostatin-induced modulation of plasminogen activation with concomitant loss of focal adhesions and actin stress fibers in cultured human endothelial cells [J].Cancer Res,2001,61 (17):6511-6516.
  • 10Macdonald N,Sivers JW,Narum D L,et al. Endostatin binds tropomyosin,a potential modulator of the antitumor activity of endostatin [J].J Biol Chem,2001,276:25190-25196.

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  • 1张耀洲,吴祥甫.内皮抑素研究进展[J].生物技术通报,2005,21(1):1-5. 被引量:2
  • 2邓靖宇,何生.内源性血管生成抑制因子的研究进展及在肝癌中的应用前景[J].中国普外基础与临床杂志,2006,13(2):184-186. 被引量:1
  • 3Folkman J.Tumor angiogenesis:therapeutic implication[J].N Engl J Med, 1971,285(21): 1182-1 186.
  • 4O'Reilly MS,Boehm T,Shing,ct al.Endostatin: an endogenous inhitbior of angiognesis and tumor growth[J].Cell,1997,88(2):277-285.
  • 5Dixelius J,Larsson H, Sasaki T, et al.Endostatin induced tyrosine kinase sigmaling through the Shb adaptor protein regulates endothelial cell apoptosis[J]. Blood, 2000,95(11):3403-3411.
  • 6Kim YM, Jang JW, Lee OH ,et al.Endostatin inhitbis endothelial and tumor cellular invasion byblocking the activation and catalytic activity of matrix metalloproteinase[J].Cancer Res,2000,60(19):5410-5413.
  • 7Schuppan D,Cramer T, Bauer M ,et al.Hepatocytes as a source of collagen type Ⅹ ,Ⅷ endostatin[J].Lancet, 1998,352(9131):879-880.
  • 8Homer JJ,Greenman J,Stafford ND,et al.Angiogenic cytokines in serum and plasma of patients with head and neck squamous cell earcimona[J]. Clin Otolaryngol,2000,25(6):570-576.
  • 9Burke PA,DeNardo SJ.Antiangiogenle agents and their promising potential in combined therapy[J].Crit Rev Oneol Hematol, 2001,39(1-2): 155.
  • 10Yokoyama Y, Dhanabal M, Griffioen A,et al. Synergy between angiostatin and endostatin: inhibition of ovarian cancer growth [J].Cancer Res,2000,60:2190-2196.

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