期刊文献+

心房颤动病因研究及治疗 被引量:13

Research of Etiology and Treatment in Atrial Fibrillation
下载PDF
导出
摘要 心房颤动是一种常见的心血管疾病,在心脏病学中是一种最有争议的心律失常。病因目前我们仍然不清楚,但有提示认为:基因与心房颤动有相关性。离子流改变是人为引起心房颤动后产生的基因表达水平改变,而不是心房颤动本身产生的原因。电生理机制可能参与了心房颤动的发生。C反应蛋白是炎症系统的标志物,它不仅和心房颤动有关而且也能预测病人未来发生心房颤动的危险。这里还将对心房颤动的诊断和治疗现状做一个概述。 Atrial fibrillation is a common cardiovascular disease.It is the most arguable arrhythmias.Etiological factor is still not clear at present.But somebody think there are correlation between gene and atrial fibrillation.The change of ion current is the change of gene expression level after people-inducing atrial fibrillation,not the cause of atrial fibrillation itself.Electrophysiological mechanism probably participate in occurrence of atrial fibrillation.C-reactive protein is a sign of inflammatory system.It is not only in relation to atrial fibrillation but also can predict danger of patients occurenc atrial fibrillation in future.Here will be a overview about diagnosis and therapeutics of atrial fibrillation in the present state,too.
出处 《心血管病学进展》 CAS 2005年第2期178-180,共3页 Advances in Cardiovascular Diseases
关键词 心房颤动 诊断和治疗 病因研究 心脏病学 常见 电生理机制 炎症 基因表达水平 标志物 Atrial fibrillation Etiology Diagnosis Therapeutics
  • 相关文献

参考文献18

  • 1Wolff L.Familial auricular fibrillation[J].N Engl J Med,1943,229∶396-398.
  • 2Brugada R,Tapscott T,Czernuszewicz GZ,et al.Identification of a genetic locus for familial atrial fibrillation[J].N Engl J Med,1997,336:905-911.
  • 3Brugada R,Robert SR.Molecular biology and atrial fibrillation[J].Curr Opin Cardiol,1999,14:269-273.
  • 4Lai LP,Su MJ,Yeh HM,et al.Association of the human minK gene 38G allele with atrial fibrillation:evidence of possible genetic control on the pathogenesis of atrial fibrillation[J].Am Heart J,2002,144(3):485-490.
  • 5Chen YH,Xu SJ,Bendahhou S,et al.KCNQ1 gain-of-function mutation in familial atrial fibrillation[J].Science,2003,299(5604):251-254.
  • 6Charron P.Genetic features of atrial fibrillation[J].Ann Cardiol Angeiol,2003,52(4):254-257.
  • 7Yue LX,Melnyk P,Gaspo R,et al.Molecular mechanisms underlying ionic remodeling in a dog model of atrial fibrillation[J].Circ Res,1999,84:776-784.
  • 8Yue L,Feng J,Gaspo R,et al.Ionic remodeling underlying tachycardia-induced atrial fibrillation in dogs[J].Circulation,1996,94:592.
  • 9Gaspo R,Bosch RF,Bou-Abboud E,et al.Tachycardia-induced changes in Na+ current in a chronic dog model of atrial fibrillation[J].Circ Res,1997,81:1045-1052.
  • 10Feng J,Yue L,Wang Z,et al.Ionic mechanisms of regional action potential heterogeneity in the canine right atrium[J].Circ Res,1998,83:541-551.

同被引文献85

引证文献13

二级引证文献32

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部