摘要
检测了７０名氯丁二烯（ＣＢＤ）作业工人和３０名非接触毒物人员的细胞免疫、红细胞免疫和体液免疫。与正常对照相比，ＣＢＤ作业工人Ｔ淋巴细胞亚群ＣＤ３、ＣＤ４细胞百分率降低，ＣＤ８细胞百分率升高，ＣＤ４／ＣＤ８比值降低；红细胞免疫功能降低，免疫调控发生紊乱；免疫球蛋白ＩｇＧ及补体Ｃ３降低。结果表明，ＣＢＤ对机体具有明显的兔疫毒性。
Immune functions were detected in 70 workers exposed to chlorobutadiene(CBD) and 30 workers unexposed to any kind of poison(the control group). By comparison with the control group the persentage of CDa and CD4 in Tlymphocyte subpopulation of the workers exposed to CBD were decreased, the persentage of CDs increased, CD4/CD8 ratio decreased;red-cell immune functions were decreased and immunoregulation was disordered; IgG and Complement C3 were decreased. The results showed that there was a obvious immuntoxicity in the workers exposed to CBD.
出处
《卫生毒理学杂志》
CSCD
1994年第3期158-159,163,共3页
Journal of Health Toxicology
关键词
氯丁二烯
T淋巴细胞亚群
红细胞免疫粘附
Chlorobutadiene
T Lymphocyte subpopulation
Red cell immune adherene
Regulatory factors
Immunoglobulin.
