职业性铅作业工人神经行为学研究

Neurobehavioral studies on lead workers

用WHO神经行为学核心成套测试方法对某铅熔炼厂39名铅作业工人进行了神经行为学检查，结果表明，接触组情感状态、简单反应时、数字广度、数字译码、视觉保留、目标追踪及圣他·安那提转敏捷度测试成绩与对照组比较均有显著改变，提示长期低浓度铅接触可致高级神经功能紊乱。多元回归分析提示接触组工人部分神经行为功能改变与空气铅浓度及工人血铅有关，说明控制作业场所空气铅浓度是减少工人神经行为功能损害的重要途径。

A set of neurobehavioral core test battery(NCTB) was used to study the effects of occupational expo sure to lead at lower level on 39 lead workers and an age and education matched referential group.The Re sults showed some impairments in lead workers.More fatigue,confusion,tension and less vigor are the char acteristics of the mood state in lead exposed group.Sustained attention and psychomotor task were per formed more slowly；visual perceptual memory and motor function were affected too.Multiple linear regres sion analysis showed that the simple reaction time,Sante Ann manual dexterity test and some aspects of mood state were significantly related to lead concentration in air and workers'blood.Therefore,to control air lead concentration at very lower level should be an important approach to prevent the development of neuro toxicity of lead.