摘要
电喷雾质谱是目前应用最广泛的生物质谱技术之一。复杂生物基质对质谱分析的选择性和准确性提出挑战 ,迫切需要在质谱方法学上有所发展。本文介绍具有广泛应用前景的几种电喷雾质谱新方法的原理和特点及若干应用实例 。
The electrospray ionization mass spectrometry(ESI MS)was one of the most widely applicable bio-MS technologies.The complexity of biological matrices challenged the selectivity and accuracy of MS analysis,and demanded the development of MS methodology.Therefore several novel approaches based on ESI MS,which had a wide potential,were introduced with respect to their principle and merits as well as real examples in application.The trend of bio-MS technology and its future application in the field of bio-analytical chemistry were prospected.
出处
《现代仪器》
2005年第1期5-7,4,共4页
Modern Instruments
基金
国家 973项目 ( 2 0 0 1CB5 10 3 0 6)
科技部十五攻关项目 ( 2 0 0 4BA72 1AB)资助
