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甲状腺疾病与雌激素受体及孕激素受体的关系 被引量:1

RELATIONSHIP BETWEEN ESTROGEN RECEPTOR, PROGESTERONE RECEPTOR AND THE DISEASES OF THE THYROID
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摘要 用亲和组化法检测90例甲状腺疾病组织的雌、孕激素受体。发现甲状腺腺癌的雌激素受体和孕激素受体含量明显高于良性疾病,两者比较差异有极显著意义。胎儿型腺瘤与胶性腺瘤的孕激素受体含量差异显著。结果说明雌、孕激素与甲状腺腺癌发生有关,孕激素可能有阻碍细胞分化的作用。 0 thyroid tissues from the thyroid diseases were examined by the affinity-histochemistrymethods to detect the relationship between the estrogen receptor(ER)and progesterone receptor(PgR)and the diseases of the thyroid gland(P<0.01).The results showed that the value of ER,PgR in the thyroid carcinoma was significantly higher than that in the benign diseases of thethyroid gland.There was significant difference between them.The value of PgR in fetal adenomawas significantly higher than that in the colloid adenoma. These results indicated that ER,PgRwere related to the carcinogenesis of the thyroadenoma and PgR could interfere in the celldifferentiation.
出处 《温州医学院学报》 CAS 1994年第1期13-15,共3页 Journal of Wenzhou Medical College
关键词 甲状腺疾病 受体 雌激素 孕激素 thyroid disease receptor estrogen progesterone
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