成人原发性肾小球疾病205例病理与临床分析

PATHOLOGY AND CLINIC OF ADULT PRIMARY GLOMERULAR DISEASE IN 205 RENAL BIOPSIED CASES

２０５例成人原发性肾小球疾病肾活检结果显示系膜增生性肾小球肾炎（ＭｓＰＧＮ）最常见，占４０．５／，其次是微小病变肾病（ＭＣＤ），占１４，６％，局灶节段性肾小球硬化（ＦＳＧＳ）占１２，７％。临床表现以肾病综合征最常见共１０２例，占５０．０％，其中以ＭｓＰＧＮ和ＭＣＤ居多，分别占３６．３％和２９．４％。

he clinical and pathological features of primary glomerular disease were anaIysed in 205 aduIt re-nal biopsied cases. PathoIOgically,mesangial proliferative glomerulonephritis(MsPGN)was the mostcommon type,accounting ror 40.5%of the whole series.The others were minimal change disease(MCD) l4.6%,focal segmental glomerulosclerosis(FSGS)12.7%. Clinically,there were l02cases of nephortic syndrome(50.0%)which was the most common clinical manifestation of primaryglomerular disease. MsPGN and MCD Were the chief pathomorphologicaI types of this syndrome,ac- counting for 36.3%and 29.4%respectively.