肝动脉药物灌注加栓塞治疗致胆囊炎机理研究

Mechanism of cholecystitis caused by transcatheter hepatic artery infusion and embolization

肝癌患者作肝动脉药物灌注加栓塞治疗引发胆囊炎并发症者并非少见，对它的机理研究发现胆囊血供受阻是其主要原因。动物实验与电子显微镜观察显示在治疗早期药物与栓塞物可引起血管平滑肌的退变、坏死，以及小动脉壁内皮细胞脱落与血管阻塞等病理改变。

Transcatheter hepatic artery infusion and embolization for treatment of hepatic carcinoma was often complicated with cholecystitis. It was found that its main cause was devascularization of the gallbladder. Animal experiments and electromicroscopic examination showed that the medicine and bolus might cause degeneration and necrosis in vascular smooth muscles, shedding of endothelial cells in arteriolar wall and vascular blocking.