摘要
目的评价曲美他嗪治疗不稳定型心绞痛的临床疗效。方法采用随机、单盲对照及组间对照,将92例不稳定型心绞痛患者分为常规治疗组(对照组46例)和曲美他嗪组(46例)。后者服用曲美他嗪20mgtid,余用药同对照组,疗程均为12周。观察两组治疗前后临床疗效,心电图及动态心电图变化。结果治疗后曲美他嗪组总有效率89.1%,对照组总有效率67.4%,心电图改善率分别为74.0%和52.2%,动态心电图缺血发作次数、总缺血时间和总缺血面积均有显著改善。结论曲美他嗪治疗不稳定型心绞痛疗效确切,值得临床推广使用。
Objective To study the effects of trimedazidine on improving UAP in patients. Methods Ninty-two patients with UAP were divided into trimedazidine group (n=46)and control group (n=46) with random,single blind contrast to evaluate the clinical effect and change of the electrocardiogram and dynamic eletrocardiogram. Results No adverse reaction were found related to the drug. Conclusion Trimedazidine can improve the UAP in patients and is valuable to be spread broadly in clinic.
出处
《中国心血管病研究》
CAS
2005年第3期212-213,共2页
Chinese Journal of Cardiovascular Research
关键词
曲美他嗪
不稳定型心绞痛
Trimedazidine
Unstable angina pectoris(UAP)
