不同方法治疗大动脉炎致主动脉瓣关闭不全疗效分析

Analysis of different treatment for aortic regurgitation caused by aortitis

目的评价不同治疗方法对大动脉炎致主动脉瓣关闭不全的疗效和预后的影响。方法380例住院大动脉炎患者,合并中到重度主动脉瓣关闭不全38例,分为内科保守治疗和外科手术治疗两组,随访1～96个月。结果内科保守治疗22例,死亡4例,病情加重6例;手术治疗16例,死亡4例,病情加重2例。两组治疗结果差异无显著意义(P>005)。结论外科手术治疗对患者的生存并不比内科保守治疗更有益,但也可能是病例数较少,造成统计上无差异。

Objective To evaluate the effect and prognosis of two different therapeutic methods for aortic regurgitation caused by aortitis.Methods 380 in-patients with aortic regurgitation caused by aortitis were investigated retrospectively.Among them,38 patients had middling to severe aortic regurgitation,and then were divided into the following 2 group:medical conservative treatment and surgical treatment.Results 22 patients were given medical conservative treatment.In this group,4 patients died and 6 patients worsened;16 patients underwent surgical treatment.4 patients died,2 patients deteriorated.There is no significant difference between two therapeutic methods(P>0.05).Conclusion As far as the survival race is concerned,surgical treatment is not better than medical conservative treatment,insufficient cases may be the reason,further than follow-up is necessary.