氟康唑治疗慢性阻塞性肺疾病继发呼吸道真菌感染三种给药方法的成本效果分析

Cost-effectiveness analysis of three methods of fluconazole for chronic obstructive pulmonary disease complicated with fungus infection in hospital

目的探讨治疗慢性阻塞性肺疾病(COPD)继发呼吸道真菌感染的合理用药方法。方法选择60例COPD继发呼吸道感染患者分为三组A组氟康唑02静滴,qd×10d;B组氟康唑02静滴,qd×3d,后改为015口服,qd×7d;C组氟康唑015口服,qd×10d。运用经济学的成本效果方法进行分析评价。结果三种不同给药方法的成本效果比分别为5538、2783、1602。结论口服氟康唑为治疗COPD继发呼吸道真菌感染的最佳方法。

Objective To provide a rational arrangement for chronic obstructive pulmonary disease(COPD) complicated with fungus infection with our limited cost.Methods 60 cases of COPD complicated with fungus infection in hospital were selected:A group(fluconazole,200mg,ivdrip,qd×7d);B group(fluconazole,200mg ivdrip qd×3d,then 150mg po,qd×7d);C group:fluconazole,150mg po,qd×10d).The plans were evaluated by pharmacoeconomic cost-effectiveness analysis.Result The cost-effectiveness ratio of three methods was 55.38,27.83,16.02,respectively.Conclusion Methods C is the best one.