胃肠道癌卵巢转移46例临床病理特点及预后分析

Clinicopathologic features and prognosis of metastatic ovarian carcinoma from the stomach or colon cancer.

目的 探讨胃肠道癌卵巢转移的临床病理特点、治疗措施和影响预后因素。方法 回顾性分析江西医学院第二附属医院 1980年 1月至 2001年 6月收治的 46例胃肠道癌卵巢转移的临床资料。结果 原发胃癌27例,大肠癌 19例,以双侧卵巢转移多见。原发灶多为低分化腺癌或印戒细胞癌,常侵犯浆膜。临床分期以中晚期居多(Ⅲ期、Ⅳ期胃癌 23例,DukesC、D期大肠癌 13例)。该病预后较差。结论 对于女性胃肠道肿瘤应注意有无卵巢转移,对有卵巢转移者应在根治性切除原发灶的同时一并切除子宫及双侧附件,术后采用综合治疗有助于改善预后。

Objective To investigate the clinicopathologic features,tre atment and prognosis of metastatic ovarian carcinoma.Methods The clinical data of 46 patients with metastatic ovaria n carcinoma at the Second Affiliated Hospital of Jiangxi Medical College from Ja n.1980 to Jun.2001 were reviewed. Results The primary carcinoma included 27 cases of stomach can cer and 19 cases of colon cancer.Ovarian metastasis is often found bilateral,esp ecially in premenopausal stage,low-differentiated or ring-cell adenocarcinoma, tumors at advanced stage are prone to metastasize to ovary,and the patient’s pr ognosis is usually poor.Conclusion It is mandatory to inspect the ovary during a laparo tomy of stomach or colon tumor woman.The stomachoscopy and colonoscopy must be o ffered to the patient who is suspected to have metastatic ovarian carcinoma,pati ents with ovarian metastases should undergo additional uterectomy plus bilateral oophorectomy.