不同锌源对断奶仔猪免疫和抗氧化作用的影响

Effect of Different Zinc Source on Immune and Antioxidation in Weanling Swine

选用 1 4 4头断奶仔猪 ,随机分成 4组 :一组为对照 ,饲喂添加氧化锌 1 0 0 mg/kg的日粮 ,另 3组分别饲喂添加氧化锌 30 0 0 m g/kg、蛋氨酸锌 1 0 0 m g/kg和纳米氧化锌 30 0 m g/kg的日粮 ,进行为期 5 2 d的饲养试验 ,以研究不同锌源对断奶仔猪消化和免疫功能的影响。结果表明 :高剂量氧化锌可提高血清中 Ig A的含量 5 .0 7%(P<0 .0 5 ) ,高剂量氧化锌和纳米氧化锌可使血清中免疫球蛋白 Ig M含量分别提高 2 .97%(P<0 .0 5 )和 5 .6 7%(P<0 .0 1 ) ;蛋氨酸锌可使血清中SOD活性比对照组提高 1 .36倍 (P<0 .0 1 ) ,高剂量氧化锌和蛋氨酸锌可分别使肝脏中 SOD活性提高 2 8.2 0 %(P<0 .0 5 )和 2 9.33%(P<0 .0 5 ) ;高剂量氧化锌、蛋氨酸锌和纳米氧化锌均可提高肝脏组织中金属硫蛋白 (MT)

One hundred and forty four piglets were divided into four groups on breed,the treatment groups received the same basal diet,supplemented with 100 mg/kg ZnO(control),(3 000) mg/kg ZnO,100 mg/kg Zn-Met and 300 mg/kg nanometer ZnO respectively.The results of immune investigation showed that (3 000) mg/kg ZnO increased IgA level by 5.07%(P<0.05) as compared with the control,the (3 000) mg/kg ZnO and 100 mg/kg nanometer ZnO increased the IgM level in serum by 2.97%(P<0.05) and 5.67%(P<0.01).The analysis of SOD in serum and liver showed that adding 100 mg/kg Zn-Met increased the SOD level in serum by 1.36-fold as compared with control,and adding (3 000) mg/kg ZnO and 100 mg/kg Zn-Met also increased the SOD level in the liver by 28.20% and 29.33%(P<0.05).The analysis of liver samples showed that three treaments increased the MT concentration in the liver.