大鼠游泳运动疲劳模型建立的研究

The Establishment of Exercise-induced Fatigue Model in Rats

目的 采用 10d递增负荷的游泳运动方式建立大鼠运动疲劳模型。结果 此运动模型动物出现脱毛现象 ,且神情倦怠 ,食欲降低 ,运动能力下降、对外界刺激反应迟钝 ,探究行为明显减少 ;运动第 7d与第 10d运动组体重平均值均较对照组显著下降 ;血清CK值运动后 12h和 2 4h与对照值相比有显著性增高 ;血尿素值运动后即刻、运动后 12h与对照值相比显著增高。结论 本实验动物模型是可靠的 ,可用于运动疲劳机制的实验性研究。

After ten days loading-increasing swimming exercise,the rats showed that the co nditi on of fatigue, and on the 7th and 10th day, the body weight is decreased signif icantly(P<0.05,P<0.01).In the 12SG and 24SG, the CK are increased significantly(P<0. 0 1).In the 0SG and 12SG, the BU are increased significantly(P<0.05).Both t he behavior and chemical index showed that the rats are in the condition of fatigue.The model is suitable for the us e of the experiments of exercise-induced fatigue.