摘要
利用绞股蓝总皂甙(GP)对5株不同的体外培养实体癌细胞株增殖的影响,发现GP的抑瘤作用随细胞株来源不同有明显的差异。当GP浓度为1～10mg/L时,对肺癌细胞株A549、Calu 1、592/9的抑制作用明显强于宫颈癌Hela S_3及结肠腺癌Colo 205,而同样浓度的GP却能促进正常人的混合淋巴细胞反应。
The suppression effect of Gypeno-sides (GP) on cultured carcinoma cells was observed in the present experiment. We found the suppres-sion effect varied with different cell lines. With 10 mg/L GP. the proliferation of lung carcinoma cellsA549, Calu 1, 592/9 were suppressed much morestrongly than cervical carcinoma Hela S3 and colonadnocarcinoma Colo 205. Meanwhile, instead sup-pression effect, GP could enhance mixed lymphocytereaction at the same concentration.
出处
《西安医科大学学报》
CSCD
1994年第4期346-348,共3页
Journal of Xi'an Medical University(Chinese)
关键词
绞股蓝
癌细胞株
细胞增殖反应
淋巴细胞
总皂甙
gypenosides
carcinoma cell lines
cell proliferation
mixed lymphocyte reaction
