薯蔓黄酮降血糖作用研究

Blood-glucose Lowering Effects of Flavonoids Extracted from Sweet Potato Vines

研究了薯蔓黄酮(FSPV)对四氧嘧啶致糖尿病小鼠血糖水平的影响。采用昆明种小白鼠分组,分别以FSPV、优降糖或生理盐水灌胃,测定正常小鼠及四氧嘧啶糖尿病小鼠的血糖水平。实验结果表明:各剂量FSPV均能显著降低四氧嘧啶致糖尿病小鼠的血糖水平,但对正常小鼠的血糖水平无显著影响。结论:FSPV具有显著的降血糖作用,是一种值得开发利用的植物黄酮。

To observe the blood-glucose lowering effects of flavonoids extracted from sweet potato vines (FSPV) on experimental diabetic mice, the mice were divided into different groups. Each group was given FSPV or glybenclamide or normal Saline, respectively. The concentration of serum glucose were determined respectively in normal control groups and diabetic mice groups induced by alloxan. Three doses of FSPV could remarkably decrease the serum glucose of diatetic mice. On the other hand, it was found that FSPV had no significant influence on the serum glucose level of normal mice. Conclusion: FSPV had significant effects of lowering blood-glucose action on diabetic mice and was probably worthy to be developed into medicines for diabetes.