摘要
作者观察了１０例室间隔缺损并中、重度肺动脉高压肺组织超微结构的改变：①肺泡隔纤维化、胶原纤维增生；②肺泡Ⅱ型细胞显著增生，胞质内见大量线粒体，粗面内质网，板层小体增多其内容丢失；③肺泡－毛细血管腔厚度增加；④肺血管基膜增厚或扩张。可能是因为长期高流量、高压力冲击下，肺血管发生结构性改变。
The electromicroscopic observation of lung Biopsy material was carried out in 10 patients with ventricular septal defect(VSD)with middle and severe pulmonary hypertension (pH).These observations suggest:① alveolar wall fibrosis and increase in collagen fibers;②increase in type 2 pneumonocytes and increase in mitochondria, rough endoplasmic reticulum and lamellar body in their cytoplasm;③thickening of alveolus-capillary;④ thickening or dilating of the capillaries endothelial. basement membrane. The structural change is because pulmonary blood vessel is pounded by blood flow that is hypervolemic and hypertensive.
出处
《西安医科大学学报》
CSCD
1994年第1期15-17,共3页
Journal of Xi'an Medical University(Chinese)
关键词
室间隔缺损
肺动脉高压
超微结构
ventricular septal defect(VSD)
pulmonary hypertension(pH)
lung ultrastructure
alveolar wall
mitochondria
endoplasmic reticulum
lamellar body
