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TOB/BTG家族的结构、功能及其与恶性肿瘤关系 被引量：1

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作者 吴殿超 周总光 陈尧
机构地区 四川大学华西医院 四川大学华西医学中心基础与法医学院
出处 《四川医学》 CAS 2005年第3期249-250,共2页 Sichuan Medical Journal
基金 国家杰出青年基金 (3992 50 32 )
关键词 TOB/BTG 恶性肿瘤 抗增殖
分类号 R730.2 [医药卫生—肿瘤]
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参考文献14

  • 1Matsuda S, Rouault J, Magand J, et al. In search of a function for the T1S21/PC3/BTG1/TOB family[ J]. FEBS Lett, 2001,497: 67 ～ 72.
  • 2Rouault JP, Rimokh R, Tessa C, et al. BTG1, a member of a new family of antiproliferative genes[ J]. EMBO J, 1992,11:1663 ～ 1670.
  • 3Rouault JP,Falette N,Guehenneux F, et al .Identification of BTG2,an antiproliferative p53-dependent component of the DNA damage cellular re sponse pathway[J]. Nat Genet, 1996,14:482 ～ 486.
  • 4Yoshida Y, Matsuda S, Lkematsu N, et al. ANA a novel member of Tob/BTG1 family, is expressed in the ventricular zone of the developing central nervous system[ J]. Oncogene, 1998,16: 2687 ～ 2693.
  • 5Matsuda S, Kawamura-Tsuzuku J, Ohsugi M, et al. Tob, a novel protein that interacts with p185erbB2 is associated with anti-proliferative activity[J]. Oncogene, 1996,12:705 ～ 713.
  • 6Walden PD, Lefkowitz GK, Ficazzola M, et al. ldetification of genes associ ated with stromal hyperplasia and glandular atrophy of the prostate by mR NA differential display[ J]. Exp Cell Res, 1998,245:19 ～ 26.
  • 7Corjay MH, Kearney MA, Munzer DA, et al. Atiproliferative gene BTG1 is highly expressed in apoptotic cells in macrophage-rich areas of advanced lesions in Watanabe heritable hyperlipidemic rabbit and human[J]. LabInvest, 1998,78: 847 ～ 858.
  • 8Montagnoli A, Guardavaocaro D, Starace G, et al. Overexpression of the nerve growth factor-inducible PC3 immediate early gene is associated with growth inhibition[ J]. Cell Growth Differ, 1996,7:1327 ～ 1336.
  • 9Guardavaccaro D, Corrente G, Covone F, et al. Arrest of G (1) S progression by the p53-inducible gene PC3 is Rb dependent and relies on the inhibition of cyclin D1 transcription[J]. Mol Cell Biol, 2000, 20:1797 ～1815.
  • 10Lim lK,Lee MS,Ryu MS, et al.A Induction of growth inhibition of 293cells by downregulation of the cyclin E and cyclin-dependent kinase 4 proteins due to overexpression of TIS21 [ J]. Mol Carcinog, 1998,23:25 ～ 35.

同被引文献30

  • 1Xin Wu, Nan Ding, Wentao Hu, et al. Down- regulation of BTG1 by miR -454 -3p enhances cellular radiosensitivity in re- nal carcinoma cells [J]. Radiation Oncology, 2014, 9: 179.
  • 2Zhang H, Tang J, Li C, et al. MiR-22 regulates 5 -FU sensitivity by inhibiting autophagy and promoting apoptosis in colorectal cancer cells [J]. Cancer Letters, 2015, 356 (2 PtB) : 781 -790.
  • 3Hata K, Nishijima K, Mizuguchi J. Role for Btgl and Btg2 in growth arrest of WEHI -231 ceils through arginine methylation following membrane immunoglobulin engagement [J]. Exp Cell Res, 2007, 313 (11): 2356-2366.
  • 4Bornscheinj, Rokkast, Selgradtm, et al. Gastric cancer: clini- cal aspects, epidemiology and molecular background [ J ]. Heli- cobacter, 2011, 16 (sl): 45-52.
  • 5Correiam, Machadojc, Ristimkia. Basic aspects of gastric cancer [J]. Helicobacter, 2009, 14 (Suppl 1): 36-40.
  • 6Kanda M, Sugimoto H, Nomoto S, et al. B -cell translocation gene 1 serves as a novel prognostic indicator of hepatocellular car- cinoma [J]. International Journal of Oncology, 2015, 46 (2) : 641 -648.
  • 7Sun GG, Wang YD, Cheng YJ, et al. The expression of BTG1 is downregulated in nasopharyngcal carcinoma and possibly associ- ated with tumour metastasis [J]. Mol Biol Rep, 2014, 41 (9) : 5979 -5988.
  • 8Lu YF, Sun GG, Liu Q, et al. BTGlexpression in thyroid car- cinoma: diagnostic indicator and prognostic marker [ J ]. Int J Oncol, 2014, 45 (4) : 1574 -1582.
  • 9Sun GG, Wang YD, Cheng YJ, et al. BTG1 underexpression is an independent prognostic marker in esophageal squamous cell carcinoma [J]. Tumour Biol, 2014, 35 (10): 9707-9716.
  • 10Sheng SH, Zhao CM, Sun GG. BTGI expression correlates with the pathogenesis and progression of breast carcinomas [ J ]. TumourBiol, 2014, 35 (4): 3317-3326.

引证文献1

四川医学
2005年 第3期

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