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核受体共激活因子及其转录调节 被引量:1

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摘要 共激活因子是包括核受体在内的转录因子调节基因转录过程中所需要的。它们通常以复合物的形式存在,能介导核受体和基础转录机器成分之间的相互作用,并能修饰组蛋白,导致染色质重构,从而促进基因表达。共激活因子本身的特异性和活性也受到各种共价修饰的调节。
出处 《国外医学(生理病理科学与临床分册)》 2005年第1期21-24,共4页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
基金 国家自然科学基金(39970161)
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