摘要
目的观察五倍子乙醇提取物对金黄色葡萄球菌(MRSA和MSSA)的体外抗菌活性。方法采用中药抑菌实验方法对五倍子乙醇提取物进行了112株金黄色葡萄球菌的最低抑菌浓度测定。结果五倍子乙醇提取物对84株耐甲氧西林的金黄色葡萄球菌(methicillin-resistantstaphylococcusaureus,MRSA)和28株甲氧西林敏感的金黄色葡萄球菌(methicillin-sensitivestaphylococcusaureus,MSSA)的MIC50、MIC90分别为0.315、0.315和0.63、0.315mg/mL。结论五倍子乙醇提取物对金黄色葡萄球菌(84株MRSA和28株MSSA)具有较强的抑菌活性。
Objective To evaluate the in- vitro antibacterial activity of e thanol- extract of Galla Chinensis against Staphycoccus aureus (S. aureus).Meth ods The minimum inhibitory concentration (MIC50) of ethanol- extract of Galla Chinensis against 112 strains of S. aureus was detected by using agar dilution method.Results The MIC50 and MIC90 of ethanol- extract of Galla Chinensis aga inst 84 strains of MRSA (methicillin- resistant staphylococcus aureus) were 0. 315, 0.315 mg/mL, and those against 28 strains MSSA (methicillin- sensitive sta phylococcus aureus) were 0.63 and 0.315 mg/mL respectively.Conclusion Ethanol - extract of Galla Chinensis has a strong antibacterial activity against S.aure us.
出处
《中药新药与临床药理》
CAS
CSCD
2005年第2期103-105,共3页
Traditional Chinese Drug Research and Clinical Pharmacology
基金
河北省中医药管理局计划内研究项目(编号2004029)
关键词
五倍子
乙醇提取物
耐甲氧西林金葡菌(MRSA)
甲氧西林敏感金葡菌(MSSA)
体外抗菌活性
Galla Chinensis, Ethanol extract
Methicillin- resistant Staphy coccus aureus (MRSA)
Methicillin- sensitive Staphycoccus aureus (MSSA)
In- vitro antibacterial activity
