除草剂NC－311中间体2－乙氧羰基氨基－4，6－二甲氧基嘧啶的合成

THE SYNTHESIS OF THE INTERMEDIATE HERBICIDENC-311-2-ETHOXYCARBAMOYL- 4 , 6-DIMETHOXYPYRIMIDINE

采用乙氧羰基异硫氰酸酯和，３－丙二酰亚胺二甲酯为原料，乙腈作溶剂，在氮气保护下，控制适当温度，合成了磺酰脲类除草剂中间体－２－乙氧端基氨基－４，６－二甲氧基嘧啶，产率由４５％提高到６５％。还探讨了反应的机理．

This paper reports the synthesis of the sulfonylurea-herbicide Intermediats-2-ethoxycarbanioyl-4 ,6-dimethoxypyrimidine by the reaction of ethoxycarbonyl isothiocyanide with 1, 3-propane diimidedimethy 1 ester. Under nitrogen we found the better reaction Conditions and thus improved the litera-ture-reported value and the yield reaches 45 % to 65% .