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浆膜腔积液的分子生物学诊断 被引量：5

Molecular biologic diagnosis of serous effusions
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摘要 浆膜腔积液良恶性的鉴别一直是困扰临床工作者的难题,细胞学检查为其诊断的金标准,但敏感度不高。近年来分子生物学指标和方法被用来诊断浆膜腔积液的良恶性,显示出较好的应用前景。
作者 操凤 张焜和
机构地区 江西医学院第一附属医院消化内科
出处 《国外医学（肿瘤学分册）》 2005年第3期199-201,共3页 Foreign Medical Sciences (Cancer Section)
关键词 胸腔积液 腹水 分子生物学 诊断 鉴别
分类号 R730.4 [医药卫生—肿瘤]
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参考文献17

  • 1Winter MJ,Nagelkerken B, Mertens AE,et al. Expression of Ep-CAM shifts the state of cadherin-mediated adhesions from strong to weak.Exp Cell Res,2003,285(1) :50-58.
  • 2Nagel H, Werner C, Hemmerlein B. Real- time reverse transcriptionpolymerase chain reaction assay for GA733-2 mRNA in the detection of metastatic carcinoma cells in serous effusions. Am J Clin Pathol,2003,120(6): 888-901
  • 3Sakaguchi M, Virmani AK, Ashfaq R, et al. Development of a sensitive, specific reverse transcriptase polymerase chain reaction-based assay for epithelial tumour cells in effusions. Br J Cancer, 1999,79 (3-4) :416-422.
  • 4Davidson B, Goldberg I, Reich R, et al. AlphaV-and betal-integrin subunits are commonly expressed in malignant effusions from ovarian carcinoma patients. Gynecol Oncol,2003,90(2) :248-257.
  • 5Kitazume H, Kitamura K, Mukai K, et al. Cytologic differential diagnosis among reactive mesothelial cells, malignant mesothelioma, and adenocarcinoma: utility of combined E-cadherin and calretinin immunostaining. Cancer,2000,90(1): 55-60.
  • 6Schofield K, D' Aquila T, Rimm DL. E-cadherin expression is a sensitive and specific method for detection of carcinoma cells in fluid specimens. Diagn Cytopathol,2000,22 (5) :263-267.
  • 7Davidson B,Nielsen S,Christensen J,et al. The role of desmin and Ncadherin in effusion cytology: a comparative study using established markers of mesothelial and epithelial cells. Am J Surg Pathol,2001,25(11):1405-1412.
  • 8Davidson B, Goldberg I, Berner A, et al. Expression of membranetype 1 ,2,and 3 matrix metalloproteinases messenger RNA in ovarian carcianma cells in serous effusions. Am J Clin Patho1,2001,115 (4):517-524.
  • 9Yu CJ,Shew JY,Liaw YS,et al. Application of mucin quantitative competitive reverse transcription polymerase chain reaction in assisting the diagnosis of malignant pleural effusion. Am J Respir Crit Care Med,2001,164(7): 1312-1318.
  • 10Davidson B,Risberg B,Goldberg I,et al. Ets-1 mRNA expression in effusions of serous ovarian carcinoma patients is a marker of poor outcome. Am J Surg Pathol,2001,25 (12): 1493-1500.

同被引文献37

  • 1孙小蓉,汪键,Alfred Boecking.DNA倍体分析系统用于宫颈癌及上皮内瘤变的诊断及预测[J].中华病理学杂志,2005,34(7):435-437. 被引量：60
  • 2吴丽颖,刘邦荣,陆军,凌明德,李朋,王兴鹏.核仁组成区嗜银蛋白联合流式细胞术-DNA倍体分析对良恶性胸腹水鉴别诊断的临床价值[J].临床内科杂志,2006,23(4):242-245. 被引量：1
  • 3陶敏,李建勇,吴洁,冯薇,王耀,王爱青,马家用,王光杰.支气管冲洗和肺泡灌洗液细胞 DNA 含量分析对肺癌的诊断价值[J].中华结核和呼吸杂志,1996,19(4):222-225. 被引量：8
  • 4Auer GU, Caspersson TD, Wallgem AS. DNA content and survical in mammary carcinoma [ J ]. Anat Quant Cytol, 1980,2 (3) :161 - 165.
  • 5Osterheld MC, Liette C, Anca M. Image eytometry: an aid for cytological diagnosis of pleural effusions [ J ]. Diagn Cytopathol, 2005, 32(3) :173 - 176.
  • 6Dejmek A, Yahata N, Ohyashike K, et al. In situ telomerase activity in pleural effusions: a promising marker for malignancy[J]. Diagn Cytopathol, 2001,24(1) :11 -15.
  • 7Haroske G, Baak JP, Danielsen H, et al. Fourth updated ESACP consensus report on diagnostic DNA image cytometry[ J]. Anal Cell Pathol, 2001,23(2) :89 -95.
  • 8Osterheld MC, Liette C, Anca M. Image cytometry: an aid for cytological diagnosis of pleural effusions[J]. Diagn Cytopathol ,2005,32(3) :173-176.
  • 9Hanselaar AG. Additional techniques in serous effusions[J]. Anal Cell Pathol ,2002,24(1) :1-4.
  • 10Auer GU, Caspersson TO, Wallgren AS. DNA content and survival in mammary carcinoa[J]. Anat Quant Cytol , 1980, 2 (3):161-165.

引证文献5

二级引证文献26

国外医学（肿瘤学分册）
2005年 第3期

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