肝硬化患者血清SF、AKP及γ-GT检测的临床意义

Clinical Significance of Determined Serum Ferritin,Alkaline Phosphatase and Gamma glutamyl transpeptidce in patients with Liver Cirrhosis

目的 探讨肝硬化与血清SF、血清AKP及γ -GT的关系及临床诊断价值。方法 对 31例肝硬化患者 ,用微粒子免疫法 (MEIA)检测SF ,用化学法检测血清碱性磷酸酶AKP及γ -GT。结果 31例肝硬化患者SF、AKP及γ -GT含量与病情发展均有着密切的正相关性 ,r分别为 0 .4 5 2、0 .4 6 1、0 .30 6 ;SF含量随AKP及γ -GT含量的变化而逐步变化 ,r分别为 0 .6 5 6 ,0 .6 1 9。结论 SF、AKP及γ -GT对肝硬化的诊断有较大临床意义 ;但评价某一患者的预后时 ,需结合临床表现、肝功能、B超、肝活检及其他相关实验室检查加以全面综合分析。

Objective To discuss the relationship and clinical significance of livar cirrhosis and serum ferritin (SF),Alkaline phosphatase (AKP) and Gamma glutamyl transpeptidase (γ-GT).Methods 31 patients with liver cirrhosis were examined with Micropartical enzyme immunoassay (MEIA) for SF and with histochemical method for AKP and γ-GT.Results There was a positive correlation between the contents of SF,AKP,γ-GT and the disease actioity of liver cirrhosis.Conclusions SF,AKP and γ-GT have grent ralae in the diagnosis of liver cirrhosis Overall analysis is needed to prognostic value of liver cirrhosis combined with clinical resentation liver function B ultrasonographyu liver pathological diagnosis and ather related laboratory exam.