血清唾液酸检测癌症和良性疾病研究

Research on Diagnosis of Cancers and Benign Diseses by Means of Serum Sialic Acid

对癌症、良性肿瘤、常见病患者及健康者进行血清唾液酸（ＳＡ）检测，并对确诊或尚未确诊病例进行动态监测，结果ＳＡ正常参考值为２．０７±０．４７ｍｍｏｌ／Ｌ，性别之间无显著差别（Ｐ＜０．５）癌症组、良性疾病组、健康组之间ＳＡ依次有极显著性差别（Ｐ＜０．００１），应用ＬＲ和ＰＴＬ等指标对ＳＡ在临床应用进行系统评价，指出ＳＡ检测癌症特异性较差。且报道肾炎，尤其是急性肾炎和恙虫病ＳＡ也会显著升高，过度饮酒和抽烟也会升高，ＳＡ作为检测癌症必须动态监测，作为检测有否疾病是一种较好的试验。

This a ppeport of laboratory diagnoses of different serts of cancers andbenign diseases by means of serum sialic. Of all the cases tested,83 were cansers,18 benigntumors,97 common ailment and 169 health group.And among the cases of disease of dis-ease,55 were done under surveillance. It is first discovered that the average vaiue can alsoinc rease in the case of nepphritic and tsutsugamushi diseases. In addition positive rato is veryhigh too,The averge value is likely to rise along with excessive drinking and smoking. Thefirst systematic evaiuation of clinical practice of serum sialic acid shows,that serum sialicacid test brings about a lower result about cancer specifiaty and done under survellace are al-so needed in order to result in a better syntheses diagnose.