长沙某高校2001～2003年新生HBV感染调查分析

A Seroepidemiological Study on HBV Infection Among Freshmen of a University in Changsha from 2001 to 2003

目的 了解大学新生乙型肝炎病毒感染情况 ,为防治工作提供依据。 方法 2 0 0 1～ 2 0 0 3年新生共计6918人 ,对全部新生行肝功能与HBsAg检测 ,再对HBsAg阳性者 ,运用酶联免疫法 ,再行乙肝“两对半”测定。 结果 HBsAg阳性者 468例 ,总阳性率为 6.67% ,男女有性别差异。感染模式以“大三阳”“小三阳”为主 ,男女有性别差异。ALT升高 67例 ,男女有性别差异。 结论 为预防和控制HBV在高校内传染 ,应加强新生中HBVM及ALT的检测 ,并采取综合防预措施。

Objective To understand the infection rate of hepatitis B virus (HBV) among freshmen of college, and offer references for prevention and treatment of HBV. Method A total of 6 918 freshmen during 2001～2003 were examined with liver function and HBsAg. To those HBsAg-positive freshmen, HBsAg, HbsAb, HBeAg, HbeAb and HbcAb were detected by ELISA. Results The total positive rate of HBsAg was 6.67%(468/6 918), and the rate was higher for males than for females. The HBV infection patterns mostly included two tri-positive patterns (HBsAg+, HBeAg+, HbcAb+ and HBsAg+ HbeAb+ HbsAb+), and the rate of males and females were different. Sixty-seven had increased ALT in the examination, and there was difference between male and female. Conclusions In order to prevent and control the infection of HBV in universities, the examination of HBVM and ALT in freshmen should be intensified, and integrated measures of prevention and treatment should be taken.