等效剂量曲马多和芬太尼术后镇痛对全麻患者拔管期循环和呼吸的影响

Effect of tramal or fentanyl on circulation and respiration of general anesthesia patient managed postoperative analgesia during trachea extubation

目的比较等效剂量曲马多和芬太尼持续静脉镇痛对全麻患者气管拔管循环和呼吸的影响。方法60例ASAⅠ、Ⅱ级全麻手术病人随机分为T组和F组,分别于手术结束前30min给予曲马多或芬太尼静脉镇痛,观察拔管后1、5和10min时的SBP、HR、SpO2和PEtCO2。结果拔管时间F组长于T组,两组同期比较拔管后F组HR明显低于T组(P<0.01),SpO2较T组低,而PEtCO2较T组高(P<0.05)。结论曲马多用于全麻术后静脉镇痛几乎不影响患者的清醒及恢复,对患者拔管期间循环和呼吸的影响小于芬太尼。

To investgate the effect of Tramal and Fentanyl which were managed to postoperative analgesia by intravenous injection on circulation and respiration of general anesthesia patients during trachea extubation. Sixty patients who were accepted general anesthesia were randomly divided into two groups: Tramal group(T) and Fentanyl group(F). All patients were managed postoperative analyesia by intravenous injection of Tramal(T) or Fentanyl(F) about 30 min before the end of operation. SBP, HR, SpO2 and PEtCO2 were recorded at 1 min, 5 min and 10 min after trachea extubation. The time from the end of operation to trachea extubation in group T was shorter than that in group F (P <0.05); So were the SpO2, but the PEtCO2 were opposite (P <0.05). [Conclusion] Tramal managed to postoperative analgesia dose not affect the recovery of general anesthesia patient, and has less effects on circulation and respiration than Fentanyl.