福参 (Angelica morri Hayata)色原酮化合物的结构确定(英文)

Structural Determination of Chromone from Angelica morri Hayata

目的 :研究福参的活性成分。方法 :采用柱色谱及重结晶法进行分离纯化 ,通过光谱法进行结构鉴定 ,化学沟通法确定绝对构型。结果 :分得一个色原酮divaricatol(1)。结论 :化合物 1首次从当归属植物中分得。到目前为止 ,福参中分离到的色原酮类化合物与中药防风的基源植物防风 (SaposhnikoviadiavaricataSchischk.Syn .LedebouriellaseseloidesWolff)

AIM: To study the bioactive constituents of Angelica morri Hayata. METHODS: The constituent was isolated and purified by column chromatography and recrystallization; the structure was identified by spectral analysis, absolute configuration was determined based on chemical correlation. RESULT: One chromone was obtained and identified as divaricatol(1). CONCLUSION: Compound 1 was isolated from Angelica L. for the first time. So far, chromones from Angelica morri Hayata are similar to bioactive constituents from original plants of Radix Saposhinkoviae, Saposhnikovia diavaricata Schischkin (Ledebouriella seseloides Wolff).