抗菌药物不合理应用的典型药历分析

Analysis on Typical Drug Record of Irrational Use of Anti-infective Drugs

目的 :了解和评估我院临床不合理应用抗菌药物的主要表现类型。方法 :对2001年7月～2004年7月我院51份不合理应用抗菌药物的典型药历进行统计、分析。结果 :选药不当居首位 ,发生23人/次 ,发生率19 .5 % ;其次为无感染指征而用抗菌药物 ,发生15人/次 ,发生率12 .7 % ;越级用药居第3位 ,发生14人/次 ,发生率11 .9 % ;围手术期不规范用药和联合用药不当并列第4位 ,发生13人/次 ,发生率11 .0 %。结论 :我院临床不合理应用抗菌药物涉及多种表现类型 ,并主要分布于妇产科和儿科。应进一步加强对抗菌药应用的干预与管理。

OBJECTIVE:To understand and evaluate the main manifestations of irrational clinical use of anti-infective drugs in our hospital.METHODS:The records of 51 cases of typical irrational use of anti-infective drugs occurring from July,2001 to July,2004 in our hospital were collected and analyzed.RESULTS:Improper selection of drugs dominated over all the cases,containing 23 person/time,with the occurrence of 19.5%;Next,the cases of use of anti-infective drugs under the circumstance of no infection signs were 15 person/time,with the occurrence of 12.7%.The third manifestation was to use drugs with bypassing the limit,containing 14 person/time,with the occurrence of 11.9%.The last one was the un-standardized post-operative drug use and improper combined use of drugs,containing 13 person/time,with the occurrence of 11.0%. CONCLUSIONS:There are various manifestations of irrational use of anti-infective drugs in our hospital and they are mainly found in departments of gynecology and pediatrics.Intervention and control for use of anti-infective drugs should be strengthened.