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小儿单纯性营养不良胃肠内分泌功能的研究

Effects of protein - energy malnutrition on gastroenterol endocr ine function in children
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摘要  目的:探讨单纯性营养不良(PEM)患儿胃肠内分泌功能变化。方法:采用放射免疫分析法测定空腹和摄入液体实验餐后60 min时,外周血胃泌素(Gas)、胃动素(MTL)、生长抑素(SS)水平。结果:与对照组比较,观察组空腹和餐后 60min血中Gas和MTL水平明显降低,而SS水平则明显升高(均 P<0. 01)。结论:PEM患儿存在明显的胃肠内分泌功能紊乱。 Objective: To reveal the changes of gastroentero l endocrine function in protein - energy malnutrition(PEM) in children. Methods: The blood levels of gastrin, motilin and somatostatin befo re and after ingestion of test meal for 60 min measured by radioimmunoassay in 3 0 children with PEM and 20 age - sex matched healthy children used as the contr ols. Results: The preprandial and postprandial level of gast rin and motilin in PEM children were very significantly lower and SS was very si gnificantly higher than those of the control group( P <0 01). Compared with the preprandial level, the postprandial level of SS was very significantly highe r( P <0 01) in both groups. Conclusion: The gastroentero l endocrine function becomes disorder in children with PEM.
出处 《西南国防医药》 CAS 2005年第1期17-20,共4页 Medical Journal of National Defending Forces in Southwest China
关键词 胃泌素 胃动素 生长抑素 小儿 单纯性营养不良 内分泌功能 胃肠功能 protein - energy malnutrition, gastroenterol e ndocrine, gastrin, motilin, somatostatin
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参考文献8

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