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调节全身因素预防糖尿病性视网膜病变 被引量：3

Systemic factors of diabetic retinopathy
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摘要 糖尿病性视网膜病变(diabeticetinopathy,DR)是成年人视力丧失的主要原因之一,它与许多全身因素有关,主要包括血糖、血压和血脂等。控制血糖和血压可防止和延缓糖尿病性视网膜病变的发生和发展。近期有报道:血管紧张素转换酶抑制因子不仅能降血压,还对延缓糖尿病性视网膜病变的发展有作用;脂代谢异常与黄斑渗出及视力丧失有关;抗凝剂阿司匹林既不是糖尿病的禁忌也与预防糖尿病性视网膜病变无关;吸烟对糖尿病性视网膜病变的作用是双向的;妊娠与糖尿病性视网膜病变有关,如果在怀孕前及怀孕期血糖控制良好,对糖尿病性视网膜病变不会有长期的影响。遗传学研究使我们更了解糖尿病性视网膜病变的发病机制,有可能确定哪些是糖尿病性视网膜病变的高危因素。 Diabetic retinopathy (DR) is one of the causes of adult blindness. It relates to various systemic factors, such as blood sugar, blood pressure and blood lipids. Therefore, blood pressure and blood lipids control can prevent and delay the occurrence and development of DR. This paper reviews the influence of blood-control factors on DR, such as angiotensin-converting enzyme inhibitor (ACEI), abnormal metabolism of lipids, aspirin, smoking, pregnancy, etc.·
作者 王莺 蔡季平 唐建明
机构地区 中国上海市和平眼科医院 第二军医大学长征医院眼科
出处 《国际眼科杂志》 CAS 2005年第1期155-158,共4页 International Eye Science
关键词 糖尿病性视网膜病变 全身因素 延缓 视力丧失 血压 预防 控制血糖 成年人 双向 近期 diabetic retinopathy blood sugar blood pressure
分类号 R774.1 [医药卫生—眼科] R587 [医药卫生—内分泌]
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参考文献25

  • 1赵琴,柳林,温新富,刘志勇,徐琪.II型糖尿病患者视网膜病变与糖化血红蛋白及糖化血清蛋白的关系[J].国际眼科杂志,2004,4(2):285-287. 被引量：12
  • 2The Diabetes control and Complication Trail /Epidemiology of Diabetes and Complications Research Group. Retinopathy and nephropathy in patents with type 1 diabetes four years after a trial of intensive therapy [J]. N Engl J Med,2000;342:381-389.
  • 3Van Leiden HA, Dekker JM, Moll AC. Risk factors for incident retinopathy in a diabetic and nondiabetic population: the Hoom Study [J]. Arch Ophthalmol,2003;121:245-251.
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二级参考文献8

  • 1Kullberg CE, Abrahamsson M, Arnqvist H J, Finnstrom K, Ludvigsson J,VISS Study Group. Prevalence of retinopathy differs with age at onset of diabetes in a population of patients with Type 1 diabetes. Diabet Med,2002;19(11):924-931
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  • 3van Leiden HA, Dekker JM, Moll AC, Nijpels G, Heine RJ, Bouter LM, Stehouwer CD, Polak BC. Risk factors for incident retinopathy in a diabetic and nondiabetic population: the Hoorn study. Arch Ophthalmol,2003;121(2):245-251
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  • 5Stevens R J, Stratton IM, Holman RR. UK Prospective Diabetes Study (UKPDS58). UKPDS58-modeling glucose exposure as a risk factor for photocoagulation in type 2 diabetes. J Diabetes Complications, 2002;16(6):371-376
  • 6Saum SL, Thomas E, Lewis AM, Croft PR. The effect of diabetic control on the incidence of, and changes in, retinopathy in type 2 non-insulin dependent diabetic patients. Br J Gen Pact,2002;52(476):214-216
  • 7Kennedy DM. A comparison of automated fructosamine and HbAlc methods for monitoring diabetes in pregnancy. Ann Clin Biochem, 1998;35:283-286
  • 8Kim J, Kim KS, Shinn JW, Oh YS, Kim HT, Jo I, Shinn SH. The effect of antioxidants on glycated albumin-induced cytotoxicity in bovine retinal pericytes. Biochem Biophys Res Commun,2002;292(4):1010-6

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国际眼科杂志
2005年 第1期

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