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三维适形放射治疗胰腺癌20例疗效分析 被引量:2

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摘要 目的探讨三维适形放射治疗胰腺癌的疗效.方法20例胰腺癌患者全部采用三维适形放疗,共5次~10次,每次1 d~2 d,总剂量为40 Gy~50 Gy,设5个~7个照射野,观察肿瘤局部缓解率及总的1年、2年生存率.结果20例患者经治疗后1个月,CT、MRI复查肿瘤局部缓解率为60%(12/20),其中3例完全缓解(CR),9例部分缓解(PR),7例稳定(NC),1例进展(PD).6个月后复查结果CR4例,PR 10例,NC 5例,PD 1例,CR+PR率为70%.采用寿命表法统计生存率,总的1年、2年生存率分别为57%,21%,中位生存期为12.2个月.结论三维适形放疗对胰腺癌有较好的疗效,更远期疗效有待进一步提高.
机构地区 解放军第
出处 《肿瘤研究与临床》 CAS 2005年第1期32-33,共2页 Cancer Research and Clinic
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  • 1钟守先.积极开展胰头癌根治术——为提高五年生存率而努力[J].中华肝胆外科杂志,1998,4(5):267-268. 被引量:14
  • 2Brenner DJ, Hall EJ. Stereotactic radiotherapy of intracranial tumors: an ideal candidate for accelerated treatment. Int J Radiat Oncol Biol Phys, 1994, 28:1039-1041.
  • 3Larson DA, Flickinger JC, Loeffler JS. The radiobiology of radiosurgery. Int J Radiat Oncol Biol Phys, 1993,25:557-561.
  • 4Brenner DJ, Martel MK, Hall EJ. Fractionated regimes for stereotactic radiotherapy of recurrent tumor in the brain. Int J Radiat Oncol Biol Phys, 1991, 21:819-824.
  • 5Orton CG,Cohen L. A unified approach to dose-effect relationships in radiotherapy I: modified TDF and linear quadratic equations. Int J Radiat Oncol Biol Phys, 1988,14:549-556.
  • 6Fowler JF. Brief summary of radiobiological principles in fractionated radiotherapy. Sem Radiat Oncol, 1992, 2:16.
  • 7Ten Hakan RK, Frass BA, Lichter AS, et al. A brain tumor dose eacalation protocal based on effective dose equivalence to prior experience. Int J Radiat Oncol Biol Phys, 1998,42:137-141.
  • 8Birgir Gudjonsson. Carcinoma of the pancreas: critical analysis of costs, results of resections, and the need for standardized reporting. Am Coll Surg, 1995, 181:483-503.
  • 9Adsay NV, Conlon KC, Zee SY, et al. Intraductal papillary-mucinous neoplasms of the pancreas: an analysis of in situ and invasive carcinomas in 28 patients. Cancer, 2002, 94:62-77.
  • 10Bluemke DA, Cameron JL, Hruban RH. Potentially respectable pancreatic adenocarcinoma: spiral CT assessment with surgical and pathologic correlation. Radiology, 1995, 197:381-385.

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  • 1黄光,唐启信.适形放疗在局部晚期胰腺癌治疗中的应用[J].中国肿瘤,2004,13(11):724-726. 被引量:4
  • 2侯乘森,张景伟,王建华.常见恶性肿瘤放射治疗[M].北京:海洋出版社,1998:172-174.
  • 3沈瑜 糜福顺.肿瘤放射生物学[M].北京:中国医药科技出版社,2001.406-412.
  • 4Ralf Wilkowski,Martin Thoma,Helmut Weingandt,et al.Chemoradiation for ductal pancreatic carcinoma:Principle of combining chemotherapy with radiotherapy,definition target volume and radiation dose[J ].JOP J Pancreas,2005,6(2):216 ~230.
  • 5Dobellower R R,Merrick HW,Kunder S,et al.Adjuvant radiation therapy for pancreatic cancer:A 15 years experience[ J].Int J Radiat Oncol Biol Phys,1997,3q:31 ~37.
  • 6Anderr T,Balosso J,Louvet C,et al.Combined radiotherapy and chemotherapy (Cisplatin and 5-Fluorouracil) as palliative treatment for resected pancreatic adenocarcinoma.Results of a feasibilty study[ J].Int J Radiat Oncol Biol Phys,2000,46:903 ~ 911.
  • 7Georgescu T,Naftali Z,Varga A et al.5-fluorouracil treatment of acute pancreatitis and of pancreatic and duodenal fistulae[ J ].Rev Chir Oncol Radiol O R L Oftalmol Stomatol Chir,1990,39(1):45 ~50.
  • 8Tonetti F,Calvi A.5-Fluorouracil in the treatment of acute pancreatitis.Our experience[ J].Minerva Dietol Gastroenterol,1989,35(3):201 ~204.
  • 9于金明,于甬华,尹勇,王亚彬,徐敏,郭守芳.X射线立体定向放射治疗胰头癌13例分析[J].中华放射肿瘤学杂志,2001,10(2):125-125. 被引量:46
  • 10李金高,金和坤,Touboul E.放射治疗和化疗治疗局部晚期胰腺癌的临床分析[J].中华放射肿瘤学杂志,2001,10(4):232-235. 被引量:25

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