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免疫蛋黄抗体的研究进展 被引量：4

Research Progress on the IgY Isolated from Immunized Egg Yolk
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摘要 用特殊抗原免疫母鸡,并从免疫蛋中获取特异性抗体(IgY)已受到人们的关注。文章重点介绍了免疫蛋抗体IgY的理化性质和制备方法,并结合食源性疾病诊断与治疗以及我国食品工业发展的趋势,对IgY的应用前景进行了论述。 An attention was drawn on IgY isolated from immunized eggs laid by hens immunized with specific antigens. The physico-chemical characteristics,preparation methods and application of IgY in disease prevention, analysis and food industry were summarized in this paper.
作者 王勇德 李航 赵国华 陈宗道
机构地区 西南农业大学食品科学学院
出处 《中国食品学报》 EI CAS CSCD 2005年第1期99-103,共5页 Journal of Chinese Institute Of Food Science and Technology
关键词 免疫蛋黄抗体 特异性抗体 理化性质 应用 IgY Preparation Application Immune
分类号 R392 [医药卫生—免疫学]
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参考文献25

  • 1王德春.蛋黄免疫球蛋白制备和应用研究进展[J].国外医学（临床生物化学与检验学分册）,1995,16(1):22-24. 被引量：15
  • 2Leslie GA, Willion CL. Phylogeny of immunoglobulin structure and function. Ⅲ. Immunoglobulins of the chichen [J] .J Exp Med., 1969, 130 (6): 1 337-1 352.
  • 3Makoto S, Yoko M, Kel H, et al. Encapsulation of chicken eggs yolk immunoglobulin G (IgY) by liposomes [J] .Biosci. Biotech. Biochem., 1993, 57 (9): 1 445-1 449.
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  • 5Schiemann DA, Montgomery AL. Immune responses in chickens against Salmonella typhimurium monitored with egg antibodies [J] . Vet Microbiol., 1991, 27 (3-4): 295-304.
  • 6Hassl A, Aspock H. Purification of egg yolk immunogobulins. A two-step procedure using hydrophobic interaction chromatography and gel filtration [J] . J Immunol Method., 1988, 110 (2): 225-228.
  • 7Ntakarutimana V, Demedts P, Van Sande M, et al. A simple and economical strategy for downstream processing of specific antibodies to human transferrin from egg yolk [J] . J Immunol Method, 1992, 153 (1-2): 133-140.
  • 8Akita EM, Nakai S. Comparison of four purification methods for the production of immunoglobulins from eggs laid by hens immunized with an enterotoxigenic E. coli strain [J] . J Immunol Method, 1993, 160 (2): 207-214.
  • 9Chang H-M, Lu T-C, Chen C-C, et al. Isolation of immunoglobulin from egg yolk by anionic polysaccharides [J] . JAgi. Food Chem., 2000, 48 (4): 995-999.
  • 10Hamada S, Horikoshi T, Minami T, et al. Oral passive immunization against dental caries in rats by use of hen egg yolk antibodies specific for cell-associated glucosyltransferase of Streptococcus mutans [J] . Infect Immun., 1991, 59(11): 4 161-4 167.

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中国食品学报
2005年 第1期

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