摘要
不同厂家安定片的体外溶出度比较裴云萍,葛卫红,李建平(南京市鼓楼医院药剂科,南京210008)摘要采用转篮法研究了四个厂家6个批号安定片的体外溶出度,实验数据用威布尔分布模型拟合,求得T_d、T_(50)、m.结果表明:不同厂家生产的安定片溶出度差异...
Dissolution of six batches of diazepam tablets from four pharmaceutical ftctorleswas studied by the rotating basket method. Td, T50 and M were calculated by Weibulldistribution. We did not find a significant difference of the dissolution rates between variou.betches from the same factory but a great difference among the batches from different factories.
关键词
安定片
溶出度
威布尔
分布模型
Diazepam tablets Dissolution rate Weibull distribution